Our group uses proteomics probes to elucidate mechanisms of cellular adaptation to nutrient stress. In this talk, I'll present our work on 14-3-3z phospho-proteomics, which revealed an AMPK-ATG9A signaling axis that regulates an early step in the pro-survival process of autophagy. I'll also focus on our recent unpublished work that suggests some surprising details about the regulation of ATG9A and autophagy. Lastly, I'll discuss how these data are causing us to rethink the role of autophagy in tumor cells.
Host: Prof. Amit Reddi
Phone: 404 - 385-1428