I will describe some recent efforts in our group to develop prototype all-in-one cartridges which combine mass spec sample preparation and ionization steps in a single simple device. Mass spectrometry is a powerful analytical platform, but its application to many chemical measurement problems is limited by its complexity and the required expertise. I’ll describe new mass spectrometry approaches which significantly simplify the use of mass spec for identification and quantitation of a wide variety of applications. The problems we’ve addressed with these new methods include detection of emerging synthetic drugs in ER patients, identification of protein isoforms as a tool for developing new clinical diagnostics, and measurement of aerosolized chemical warfare agents.
Prof Facundo Fernandez (firstname.lastname@example.org)