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Prof. Suzanne Fery-Forgues

Room: 
MoSE 3201A
Date: 
Thursday, October 24, 2013 - 4:15pm to 5:15pm

Optimization of fluorescent organic nanocrystals for biological applications

The recently developed fluorescent organic nanocrystals and non-doped nanoparticles (FONs) occupy a special position among other nanoparticle systems that are used for studying a variety of fundamental processes in the life sciences.1 FONs have many advantages. The fluorescence signal-to-noise ratio is excellent, the stability is much higher than that of dispersed molecules, and surface chemistry may be performed in order to enhance biocompatibility and selectivity. However, the development of organic dyes that are fluorescent in the solid state is delicate. Understanding their particular photophysical behavior is the first step to allow proper design of FONs. The strategies used in our team to obtain strongly emissive materials will be explained, considering our recent work in various series of neutral and ionic dyes. The preparation and characterization of FONs will be evoked, as well as the first essays for bio-imaging of cell cultures, angiography 2 and in vivo imaging of small solid tumors.3

 

[1] S. Fery-Forgues. Nanoscale 2013, 5 (18), 8428-8442. [2] V. Parthasarathy, S. Fery-Forgues, E. Campioli,  G. Recher, F. Terenziani,  M.  Blanchard-Desce. Small 2011, 7, 3219-3229. [3] EuronanoMed “FONDIAG” project: Fluorescent Organic Nanocrystals for the Early Diagnosis of Esophageal and Colon Cancer

Contact Information: 

Dr. Kyril Solntsev (404-385-3117)

Map of Georgia Tech

School of Chemistry & Biochemistry

901 Atlantic Drive Atlanta, GA 30332-0400

(404) 894-4002 (phone) | (404) 894-7452 (fax)