Arturo Leone Young Investigator Award, 2012; Cell Biology of Metals Young Investigator Award, 2011; NIH NRSA Post-doctoral Fellowship, 2008-2011; Pegram Award for Excellence in Graduate Research, 2008; Distinction in the Doctoral Dissertation, 2008; Protein Design Symposium Young Investigator Award, 2007; NSF GK-12 Graduate Fellowship, 2005-2007; Miller Award for Outstanding Graduate Teaching, 2005; Distinction in the Chemistry Major, 2003; Finholt Prize in Inorganic Chemistry, 2003; Sigma Xi Grants-In-Aid-of-Research Grant, 2003; Cancer Research Training Award Fellowship, 1999-2001
Metalloproteins constitute one of the largest classes of proteins in the proteome and are involved in virtually every metabolic and signaling pathway of consequence to human health and disease. Broadly speaking, the Reddi laboratory is interested in determining the cellular, molecular, and chemical mechanisms by which metalloproteins are activated by cells, and once activated, how they communicate with other biomolecules to promote normal metabolism and physiology, placing an emphasis on systems relevant to cancer, neurodegenerative disorders, and infectious diseases. Current projects in the lab are focused on elucidating heme trafficking pathways and the role of Cu/Zn Superoxide Dismutase (SOD1) in redox signaling. Prospective students will get broad training in disciplines that span modern biochemistry, bioinorganic chemistry, biophysics, chemical biology, molecular genetics, and cell biology.