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Professor Pamela Peralta-Yahya selected 2016 Kavli Fellow

Professor Pamela Peralta-Yahya was selected as a 2016 Kavli Fellow by the National Academy of Sciences.

Prof. Reddi wins NSF CAREER award

Amit Reddi has won a five-year grant will support research on metals in the body from the National Science Foundation.

Josh Allen, BS '08, makes Forbes 30 under 30 list!

Josh Allen (BS Chemistry, 2008) has been named one of 2016’s Forbes 30 under 30 for healthcare. Josh parlayed his experience at GT into a PhD in Biochemistry and Molecular Biophysics from the University of Pennsylvania where he discovered ONC201 as a novel first-in-class anticancer agent. He is currently the Vice President of Research and Development at Oncoceutics.

Peralta-Yahya group makes cover of ACS Synthetic Biology

Research group uses G-protein coupled receptors (GPCRs) known to bind medium-chain fatty acids in mammalian cells to rapidly construct chemical sensors in yeast.

Siyuan Zhang Wins MRS Gold Graduate Student Award

Graduate student Siyuan Zhang made a big splash at the recent national meeting of the Materials Research Society.

Seminars & Events

Prof. T. Daniel Crawford - Virginia Tech
Physical Division Seminar - Tuesday, February 9, 2016 - 4:00pm - MoSE 3201A
Meeting - Tuesday, February 16, 2016 - 11:00am - MoSE 3201A
Prof. Amber Krummel - Colorado State University
Analytical Division Seminar - Tuesday, February 16, 2016 - 4:00pm - MoSE 3201A
Prof. Karen L. Wooley - Texas A&M University
Colloquium - Thursday, February 18, 2016 - 4:00pm - MoSE G011

Featured Research

Article Title
Research Authors
Emilie A. K. Warren, Tatiana S. Netterfield, Saheli Sarkar, Melissa L. Kemp, Christine K. Payne.
Citation
Scientific Reports (2015), Vol. 5, 16929
Miscellaneous Details
HERCULES: Exposome Research Center (NIEHS: P30 ES019776) at the Rollins School of Public Health, Emory University and NIH grants DP2OD006483-01 and R01AI088023 to MLK for funding

Understanding intracellular redox chemistry requires new tools for the site-specific visualization of intracellular oxidation. We have developed a spatially-resolved intracellular sensor of hydrogen peroxide, HyPer-Tau, for time-resolved imaging in live cells. This sensor consists of a hydrogen peroxide-sensing protein tethered to microtubules. We demonstrate the use of the HyPer-Tau sensor for three applications; dose-dependent response of human cells to exogenous hydrogen peroxide, a model immune response of mouse macrophages to stimulation by bacterial toxin, and a spatially-resolved response to localized delivery of hydrogen peroxide. These results demonstrate that HyPer-Tau can be used as an effective tool for tracking changes in spatially localized intracellular hydrogen peroxide and for future applications in redox signaling.

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