M.G. Finn Named Interim Chair of the School of Chemistry and Biochemistry

Finn brings a passion for education, teaching as well as research in immunology, organic synthesis and material science to the role.

Obama Intends to Name El-Sayed to President's Committee on the National Medal of Science

Chemistry Professor Mostafa El-Sayed received the National Medal of Science from President George W. Bush in 2007.

Grad Students and the Quest for the Origins of Life

Want to learn how life began? You can do that. Chemistry and Biochemistry graduate student Eric Parker tells how.

Seminars & Events

Ms. Emily S. Herman - Georgia Tech
Thesis Defense - Monday, August 4, 2014 - 11:00am - MoS&E 3201A
Mr. Cody R. Morelock - Georgia Tech
Thesis Defense - Tuesday, August 5, 2014 - 9:00am - MoS&E 4202A
Ms. Amber C. Rumple - Georgia Tech
Thesis Defense - Wednesday, August 6, 2014 - 9:00am - MoSE 3201A
Meeting - Thursday, August 14, 2014 - 11:00am - MoSE 2100F

Featured Research

Article Title
Research Authors
Offenbacher, A.., Polander, B.., Barry, B..
Citation
Journal of Biological Chemistry (2013), Vol. 288, 29056-29068
Miscellaneous Details
National Science Foundation

Photosystem II (PSII) catalyzes the light-induced oxidation of water and production of molecular oxygen.  The Mn4CaO5 cluster of PSII cycles through five sequentially oxidized Sn states.  PsbO is an extrinsic  PSII subunit (purple), which facilitates this water oxidizing cycle.  PsbO can be removed from and reconstituted to the hydrophobic photosystem II reaction center.  Reconstitution of PsbO restores oxygen-evolving activity.  In solution, PsbO exhibits structural malleability, consistent with its identification as an intrinsically disordered protein. We provide evidence in this paper that PsbO serves as a template, which organizes the PSII reaction center.  In addition, we use vibrational spectroscopy and isotope editing of PsbO to demonstrate that PsbO samples a rough conformational landscape, even when bound to its PSII target.  The results show that PsbO undergoes flash-induced hydrogen bonding changes, which are coupled with the water oxidizing cycle.  This paper gives new insight into dynamics in intrinsically disordered proteins and new information concerning the role of PsbO in photosynthetic oxygen evolution.

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