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Virtual Symposium on C-H Finctionalization

Through Georgia Tech's involvement with the NSF Center for Selective C-H Functionalization, a virtual symposium on C-H activation in organic and polymer synthesis will take place next Tuesday, March 31st at 4 PM in MoSE G021 open to ALL School of Chemistry and Biochemistry Professors, Staff, and Students. This symposium provides a unique opportunity to discover and discuss topics at the frontier of synthetic chemistry.

Seth Marder Honored by the Materials Research Society

Regents’ Professor of Chemistry Seth Marder is the straightforward choice for a singular honor, for nonlinear reasons…

Reynolds group featured on ACS Headline Science

Professor John Reynolds and group publish new research discussing their “sunglasses on demand”, a polymer coating developed with the push of a button changes color! This research has been highlighted in the latest episode of ACS Headline Science.

Charlie Liotta: The Man, The Myth, The Legend

On February 26th people from across the country gathered at Georgia Tech to honor Charlie Liotta, Regents Professor Emeritus in the School of Chemistry and Biochemistry, and his 50 years of teaching and research.

Wu wins NSF CAREER Award

School of Chemistry and Biochemistry Assistant Professor Ronghu Wu has been awarded the National Science Foundation’s most prestigious award for early-career faculty.

Shades at the Touch of a Switch

School of Chemistry and Biochemistry and Materials Science and Engineering Professor John Reynolds and colleagues develop technology for manually switchable glasses from “normal” to “cool.”

Colorful and Dynamic Workshops

School of Chemistry and Biochemistry Professor Rigoberto Hernandez and Research Scientist Kyril Solntsev are organizing unique workshops in the mountains.

Seminars & Events

Miss Christina M. Jones - Georgia Tech
Thesis Defense - Monday, March 30, 2015 - 1:30pm - MoSE 3201A
Meeting - Monday, March 30, 2015 - 4:00pm - MoSE G011
Prof. Roberto Chica - University of Ottawa
Biochemistry Division Seminar - Tuesday, March 31, 2015 - 4:00pm - MoSE 3201A
Ms. Rebecca L. Gieseking - Georgia Tech
Thesis Defense - Wednesday, April 1, 2015 - 10:00am - MoSE 3201A

Featured Research

Article Title
Research Authors
Brown, Ashley C.; Stabenfeldt, Sarah E.; Ahn, Byungwook; Hannan, Riley T.; Dhada, Kabir S.; Herman, Emily S.; Stefanelli, Victoria; Guzzetta, Nina; Alexeev, Alexander; Lam, Wilbur A.; Lyon, L. Andrew; Barker, Thomas H..
Citation
Nature Materials (2014), Vol. 13(12), 1108-1114
Miscellaneous Details
NIH (HHSN268201000043C, R21EB013743, R01EB011566 T.H.B.; R21EB013743 L.A.L.; R01HL121264 & U54 HL11230 W.A.L.), John & Mary Brock Discovery Research Fund, and DoD (W81XWH1110306 T.H.B. & W81XWH1110306 L.A.L.); NSF GRF V.S., NSF CAREER (A.A.; W.A.L.)

Clot formation is critical to the cessation of bleeding and involves the formation of a platelet plug embedded within a fibrin mesh, however, clot formation is impaired during hemorrhaging due to massive dilution of platelets and other critical clotting factors.  During clot formation, platelets bind multiple fibrin fibers thereby cross-linking and stabilizing the developing clot. We have designed platelet-like particles (PLPs) that mimic this feature of natural platelets by interacting with fibrin with high affinity and specificity at the site of injury.  Like natural platelets, these microgel-based PLPs are capable of augmenting hemostasis in vivo under physiological flow conditions, inducing wound-triggered hemostasis and decreased bleeding times in vivo in a traumatic injury model, and mediating fibrin network collapse.

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