 |
Jake D. SoperAssistant Professor Office: MS&E 1100H Phone: 404-894-4022 Fax: 404-894-7452 |
B.S., Western Washington University, 1998; Ph.D., University of Washington, 2003; NIH Postdoctoral Fellow, Massachusetts Institute of Technology, 2003-2004
George and Agnes Irene Hoving Cady Fellowship, 2000-2001; NIH Ruth L. Kirchstein Postdoctoral Fellowship, 2003-2004
Research Interests
Bioinorganic chemistry, multielectron redox catalysis and controlled radical reactions.
Increased worldwide energy consumption and environmental issues demand the development of new methods for energy generation from low-carbon and carbon-neutral feedstocks. Indeed, small-molecule transformations, including water oxidation or the selective functionalization of C-H bonds in homogeneous solution, have been termed "Holy Grails" in chemistry. These processes are in fact multielectron redox reactions. Our research efforts take inspiration from biological multielectron chemistry: Redox activity at metal species is coupled to redox transformations at "non-innocent" electron reservoir ligands for discovery of new classes of multielectron reactions.
Research in the Soper group spans the fields of inorganic, organometallic
and bioinorganic chemistry. We are skilled in the synthesis and handling
of air-sensitive materials. We use a variety of spectroscopic techniques
to characterize products and intermediates and to perform detailed mechanistic
studies. Our aims are largely twofold: i) Develop new methodologies
to effect redox transformations important to energy conversion in chemistry
and biology, and ii) Understand reaction mechanisms to guide design
of new metal catalysts and ligand architectures for multielectron redox
processes and radical reactions with stereo- and regio-control. Target
reactions include biomimetic O2 reduction, spatial and temporal control
in radical coupling for X-H bond-making and bond-breaking events, and
photo-initiated two-electron metal oxidation.
Recent Publications
"Nucleophilic aromatic substitution on aryl-amido ligands promoted by oxidizing Os(IV) centers," Jake D. Soper, Erik Saganic, David Weinberg, David A. Hrovat, Jason B. Benedict, Werner Kaminsky, James M. Mayer, Inorg. Chem., 2004, 43, 5804-5815 [cover article].
"Oxidation of TpOsIII(NH2Ph)Cl2 to TpOsIV(NHPh)Cl2 by O2," Jake D. Soper, Ian J. Rhile, Antonio G. DiPasquale, James M. Mayer, Polyhedron, 2004, 23, 323-329.
"Slow hydrogen atom self-exchange between Os(IV) anilide and Os(III) aniline complexes: Relationships with electron and proton transfer self-exchange," Jake D. Soper, James M. Mayer, J. Am. Chem. Soc., 2003, 125, 12217-12229.
"Activation of an anilido ligand for nucleophilic aromatic substitution by an oxidizing Os(IV) center," Jake D. Soper, Werner Kaminsky, James M. Mayer, J. Am. Chem. Soc., 2001, 123, 5594-5595.
"Protonation and deprotonation of TpOs(NHPh)Cl2: An unusually inert amido ligand," Jake D. Soper, Brian K. Bennett, Scott Lovell, James M. Mayer, Inorg. Chem., 2001, 40, 1888-1893.
"C-N bond formation on addition of aryl carbanions to the electrophilic nitrido ligand in TpOs(N)Cl2," Thomas J. Crevier, Brian K. Bennett, Jake D. Soper, Julie A. Bowman, Ahmad Dehestani, David A. Hrovat, Scott Lovell, Werner Kaminsky, James M. Mayer, J. Am. Chem. Soc., 2001, 123, 1059-1071.