Carolyn Bertozzi, professor of chemistry at Stanford University, and K. Barry Sharpless, a professor at Scripps Research, were two of the three winners of the 2022 Nobel Prize in Chemistry for their role in developing bioorthogonal reactions, which enable scientists to explore cells and track biological processes without interfering with the normal chemistry of the cell. That has led to development of a safe way to deliver high doses of chemotherapy without impacting nearby tissues. M.G Finn, professor and chair of the School of Chemistry and Biochemistry, and James A. Carlos Family Chair for Pediatric Technology, developed so-called click chemistry with Sharpless in 2001. It involves chemical reactions in which specific pairs of molecules react selectively with one another and ignore their environment.
Nobel laureate takes pride in success of bioorthogonal chemistry for cancer treatment